In stem cell research, there is a challenging but necessary step to validate cells throughout the whole experiments. Cellular and molecular tools are required to confirm pluripotency or to help determine the utility of cells in downstream experiments. Whether confirming cell identity and analyzing proliferation, protein levels, gene expression, or epigenetic profiles, BioCytoceuticals provides customers with comprehensive characterization service for stem cell application in disease modeling, drug discovery, and regenerative medicine, including characterization of PSCs, MSCs, and other stem cells.
| Services | Approaches | Purpose |
|---|---|---|
| Pluripotency or Lineage-specific Markers | Immunochemistry for pluripotency markers alkaline phosphatase staining; flow cytometry q-PCR and RNA-seq | To characterize iPSC, MSC, and other stem cells for expression of pluripotency or lineage-specific markers |
| Karyotyping | Comparative genomic hybridization analysis G-banding Multicolor FISH (M-FISH) analysis Chromosomal microarray analysis q-PCR analysis | To evaluate the stem cell genomic stability, chromosomal abnormalities, and copy number variants |
| Differentiation Potential | Directed differentiation into specific lineages Embryoid body (EB) formation qRT-PCR | To evaluate the ability of differentiating into three germ layers and specialized cells |
| Microbiological Contamination Testing | Mycoplasma detection Pathogen detection | To assess the purity of cells |
| DNA Fingerprinting | Short tandem repeat (STR) profiling | To assess the purity of cells |
| HLA Typing | Sequencing of HLA loci | To assess the potential for transplantation |
| Genome Sequencing | whole genome sequencing Exome gene sequencing cDNA expression analysis | To detect single nucleotide variants |
| Residual Reprogramming Factor | PCR analysis | To detect presence of plasmids- and retrovirus-reprogramming footprint |
BioCytoceuticals is an experienced and outstanding provider of stem cell characterization service. We are dedicated to providing detailed data and comprehensive service for your scientific research, and we are pleased to use our extensive experience and advanced platform to offer the best service to satisfy each demand from our customers.
If You Have Any Question About Our Service, Please Let Us Know.
Do not hesitate to contact us for this special service. Please let us know what you need and we will accommodate you. We are looking forward to working with you in the future.
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